Maternal diabetes mellitus and congenital malformation

نویسندگان

  • RUTH E. DAY
  • J. INSLEY
چکیده

Day, R. E., and Insley, J. (1976). Archives of Disease in Childhood, 51, 935. Maternal diabetes mellitus and congenital malformation: survey of 205 cases. Twenty-five out of 205 (i.e. 12%) babies born to diabetic mothers in the Birmingham Maternity Hospital in the period 1969-1974 were malformed as against 6% in a control group. The incidence was highest in the group where mothers were on insulin at the time of conception (17 out of 117, i.e. 15%). No correlation was observed between major malformation in this group and age of onset or duration of the diabetes, progressive vascular complications, maternal age, or parity. Cardiovascular malformations were over-represented.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

O-20: Maternal Age and Congenital Malformation in Yazd, Islamic Republic of Iran

Background: Congenital malformation (CM) is the major health problems in childhood because treatment and rehabilitation of children with CM is costly and complete recovery is usually impossible. For most of single primary defect the etiology is unknown. The aim of this study was to determine frequency of CM and its association with maternal age. Materials and Methods: This descriptive-observati...

متن کامل

Maternal and Fetal Outcomes in Diabetic Pregnant Women

Objective: To assess maternal and fetal outcomes in Jordanian women with known Diabetes Mellitus or Gestational Diabetes. Methods: A retrospective medical record review was conducted on 234 pregnant women who were followed at the National Center for Diabetes Endocrinology and Genetics and Gynecological Department in Jordan University Hospital between 2004 and 2009. A total of 148 subjects had G...

متن کامل

Caudal regression syndrome and popliteal webbing in connection with maternal diabetes mellitus: a case report and literature review

INTRODUCTION Most cases of caudal regression are sporadic or associated with gestational/maternal diabetes. The condition is thought to be part of a spectrum including imperforate anus, sacral agenesis and sirenomelia. Infants of diabetic mothers have two to three times the average incidence of congenital anomalies. CASE PRESENTATION We report on a 7-year-old boy from non-consanguineous famil...

متن کامل

Prenatal diagnosis of caudal regression syndrome without maternal diabetes mellitus.

Caudal regression syndrome is a rare congenital malformation with varying degrees of early gestational developmental failure. It is also known as sacral agenesis or caudal dysplasia. The cause of this malformation is thought to be defects in neuralization around the 28th day of the gestational period. Although maternal uncontrolled diabetes, genetic predisposition and vascular hypoperfusion are...

متن کامل

Feto-maternal Outcome in Patients with Gestational Diabetes Mellitus in Western India: A Two Years Follow up Study

Objective: Untreated gestational diabetes mellitus (GDM) may lead to increased risk of macrosomia, congenital anomalies, unexplained stillbirth, hypoglycemia and jaundice in newborns. This prospective study was conducted to evaluate feto-maternal outcome in women with GDM. Materials and Methods: Two hundred pregnant women underwent 75grams glucose challenge test according to Diabetes in Pregna...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2006